(一)科研項(xiàng)目
1. 生態(tài)環(huán)境部環(huán)保公益項(xiàng)目, 微生物制藥菌渣處置與利用過(guò)程風(fēng)險(xiǎn)控制技術(shù)
2. 國(guó)家自然科學(xué)基金,典型抗生素菌渣中殘留效價(jià)檢測(cè)方法的建立及菌渣脫毒工藝與機(jī)理
3. 國(guó)家自然科學(xué)基金,典型抗生素菌渣肥引發(fā)土壤細(xì)菌耐藥的劑量-效應(yīng)關(guān)系及耐藥菌環(huán)境行為
4. 生態(tài)環(huán)境部“抗生素制藥菌渣利用處置污染控制技術(shù)規(guī)范”編制
5. 科倫藥業(yè)川寧生物技術(shù)有限公司“抗生素菌渣有機(jī)肥用于工業(yè)作物定向種植綠色循環(huán)經(jīng)濟(jì)試驗(yàn)研究”
6. 山東魯抗制藥有限公司“泰樂(lè)菌素、大觀霉素、螺旋霉素、泰萬(wàn)菌素等菌渣有機(jī)肥資源化利用安全性評(píng)估”
7. 焦作健康元生物制品有限公司“頭孢菌素菌渣資源化利用安全性評(píng)估”
8. 山西大同同星制藥“土霉素發(fā)酵母液和菌渣的無(wú)害化與資源化”
9. 山東賽托生物制藥“甾體藥物發(fā)酵菌渣無(wú)害化與資源化”
10. 山東金宜善新材料有限公司“四溴雙酚A阻燃劑生產(chǎn)廢渣無(wú)害化與資源化”
(二)主要學(xué)術(shù)論文
1. Chen Cai, Huiling Liu*, Xiaohu Dai, Joann K. Whalen,Multiple selection of resistance genes in arable soil amended with cephalosporin fermentation residue,Soil Biology and Biochemistry,136(2019)107538
2. Mengmeng Wanga, Huiling Liu*,Xiangming Cheng,Hydrothermal treatment of lincomycin mycelial residues: Antibiotic resistance genes reduction and heavy metals immobilization,Bioresource Technology,271(2019)143-149
3. Yanxiang Zhang, Huiling Liu*, Yanjun Xin,Erythromycin degradation and ERY-resistant gene inactivation in erythromycin mycelial dreg by heat-activated persulfate oxidation,Chemical Engineering Journal,358(2019)1446-1453
4. Yanxiang Zhang, Huiling Liu*, Xiaohu Dai,Variations of physical and chemical properties in relation to erythromycin mycelial dreg dewaterability under heat-activated persulfate oxidation conditioning,Science of the Total Environment,687(2019)2-9
5. Chen Cai, Huiling Liu*. Application of microwave-pretreated cephalosporin mycelial dreg (CMD) as soil amendment: Temporal changes in chemical and fluorescent parameters of soil organic matter. Science of the Total Environment 621 (2018) 417-424.
6. Bo Zhang, Mengmeng Wang, Huiling Liu*. The effects of bio-available copper on macrolide antibiotic resistance genes and mobile elements during tylosin fermentation dregs co-composting. Bioresource Technology 251(2018) 230-237.
7. Mengmeng Wang, Chen Cai, Huiling Liu*. Characterization and mechanism analysis of lincomycin biodegradation with Clostridium sp. strain LCM-B isolated from lincomycin mycelial residues (LMR). Chemosphere 193 (2018) 611-617.
8. Mengmeng Wang, Bo Zhang, Huiling Liu*. Acidic hydrothermal treatment: Characteristics of organic, nitrogen and phosphorus releasing and process optimization on lincomycin removal from lincomycin mycelial residues.Chemical Engineering Journal 336 (2018) 436-444.
9. Mengmeng Wang, Bo Zhang, Huiling Liu*. Degradation of lincomycin in aqueous solution with hydrothermal treatment: Kinetics, pathway, and toxicity evaluation. Chemical Engineering Journal 343(2018) 138-145.
10. Chen Cai, Huiling Liu*, Bing Wang, Performance of microwave treatment for disintegration of cephalosporin mycelial dreg (CMD) and degradation of residual cephalosporin antibiotics, Journal of Hazardous Materials. 331(2017)265-272
11. Chen Cai, Huiling Liu*, Application of microwave-pretreated cephalosporin mycelial dreg (CMD) as soil amendment: Temporal changes in chemical and fluorescent parameters of soil organic matter,Science of the Total Environment, 621(2017)417-424
12. Chen Cai, Huiling Liu*, Bing Wang, Characterization of antibiotic mycelial residue (AMR) dewatering performance with microwave treatment,Chemosphere, 174(2017)20-27
13. Bing Wang, Chen Cai, Guomin Li,Huiling Liu* Assessing the stability in dry mycelial fertilizer of Penicillium chrysogenum as soil amendment via fluorescence excitation-emission matrix spectra: organic matter’s transformation and maturity,Environmental Science and Pollution Research, 24(2017)28258-28267
14. Bing W, Chen C, Liu H, et al. Assessing the Stability in Dry Mycelial Fertilizer of Penicillium Chrysogenum as Soil Amendment via Fluorescence Excitation-Emission Matrix Spectra:Organic Matter’s Transformation and Maturity[J]. Environmental Science and Pollution Research,(2016)20728-20738.
15. Pu Wanga, Huiling Liu*,Characterization and mechanism analysis of penicillin G biodegradation with Klebsiella pneumoniae Z1 isolated from waste penicillin bacterial residue ,Journal of Industrial and Engineering Chemistry 27 (2015) 50–58
(三)學(xué)術(shù)獎(jiǎng)勵(lì)
1. 黑龍江省科技進(jìn)步三等獎(jiǎng)1項(xiàng),
2. 黑龍江省建設(shè)廳科技進(jìn)步二等獎(jiǎng)1項(xiàng)
(四)專利
國(guó)家發(fā)明專利10項(xiàng)